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At this point, Semaglutide is usually at its full therapeutic dose, and results can become even more noticeable if paired with nutrition guidance and physical activity
doi: 10.1056/NEJMoa1008862 3 HolmanRRPaulSKBethelMAMatthewsDRNeilHA
Peak is the compounded route, offering compounded semaglutide and tirzepatide from 503A pharmacies
Before and after data was again not provided so overall % increase/decrease could not be calculated in this subgroup
Limitations and Considerations BMI cutoff used is in between the typical cutoffs for overweight and obese Limited generalizability given that the majority of patients included were Caucasian, with only 12.5% African American male predominant population studied, with only 27.7% females It remains to be demonstrated if treatment with semaglutide has a cardioprotective and preventative benefit in patients who do not have pre-existing cardiovascular disease PowellWiley TM, Poirier P, Burke LE, et al
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