Some common symptoms include: Digestive issues: Abdominal pain, bloating, diarrhea, and constipation may occur due to histamines influence on stomach acid production and gut motility
Starting conservative and adjusting based on results and tolerance remains the wisest approach
General safety Presence of acute pancreatitis within the past 180 days before the day of screening
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Pre-filled pens for tirzepatide and semaglutide need refrigeration (28 C) until first use, and even after first use most stay stable at room temperature only for a limited window UK SmPCs allow up to 30 days at no more than 30 C for an in-use Mounjaro KwikPen, up to 56 days for an in-use Ozempic pen, and up to 28 days unrefrigerated for a Wegovy pre-filled pen