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Athletes subject to anti-doping regulations face the additional consequence that the World Anti-Doping Agency (WADA) prohibits BPC-157 under the category of peptide hormones and growth factors

Therefore, while aware that the pharmacological modulation of the NRF2/ARE pathway could undeniably offer new therapeutic opportunities for diseases related to OS, we should at the same time consider that most of the currently known activators of NRF2 are not particularly specific, leading to an increased risk of off target toxic effects

doi: 10.1080/20002297.2025.2499923 48 De FilippisA.FiorentinoM.GuidaL.AnnunziataM.NastriL.RizzoA

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